Through recent research advances we are increasingly able to understand and address immune-mediated diseases. Biotechnology is yielding success in areas with a strong immunologic component, such as allergic asthma, rheumatoid arthritis, inflammatory bowel disease, psoriasis and multiple sclerosis. Nevertheless, the burden of immune-mediated diseases is still enormous, with direct and indirect costs associated with such conditions believed to exceed $100 billion in the USA alone. 
  
Expert Review of Clinical Immunology (ISSN 1744-666X) provides expert analysis and commentary regarding the performance of new therapeutic and diagnostic modalities in clinical immunology. Members of the International Editorial Advisory Panel of Expert Review of Clinical Immunology are the forefront of their area of expertise. This panel works with our dedicated editorial team to identify the most important and topical review themes and the corresponding expert(s) most appropriate to provide commentary and analysis. All articles are subject to rigorous peer-review, and the finished reviews provide an essential contribution to decision-making in clinical immunology. 
  
Articles focus on the following key areas:
• Therapeutic overviews of specific immunologic disorders highlighting optimal therapy and prospects for new medicines 
• Performance and benefits of newly approved therapeutic agents 
• New diagnostic approaches 
• Screening and patient stratification 
• Pharmacoeconomic studies 
• New therapeutic indications for existing therapies 
• Adverse effects, occurrence and reduction 
• Prospects for medicines in late-stage trials approaching regulatory approval 
• Novel treatment strategies 
• Epidemiological studies 
• Commentary and comparison of treatment guidelines 
  
Topics include infection and immunity, inflammation, host defense mechanisms, congenital and acquired immunodeficiencies, anaphylaxis and allergy, systemic immune diseases, organ-specific inflammatory diseases, transplantation immunology, endocrinology and diabetes, cancer immunology, neuroimmunology and hematological diseases. 
  
The Expert Review format is unique. Each review provides a complete overview of current thinking in a key area of clinical immunology. Comprehensive coverage is augmented by: 
  
Expert Opinion - a personal view on the most effective or promising strategies and a perspective on future prospects over the next 5 years 
Article Highlights - an executive summary cutting to the author's most critical points 
  
Many medical centers are now focusing resources specifically on immunologic disorders, and the primary literature associated with new and emerging approaches to therapy, diagnosis and outcomes research in immune-mediated diseases is burgeoning. It is no longer feasible for an individual to track and analyze all of these advances. Expert Review of Clinical Immunology provides a centralized resource of commentary and debate for this community to inform clinical and economic decision-making in healthcare delivery. 
  
We welcome suggestions or recommendations for Guest Editorials, Meeting Reports, Reviews or Drug Profiles for publication in Expert Review of Clinical Immunology . In the first instance, please contact the Commissioning Editor.

Senior Editors
Thomas Forsthuber , University of Texas at San Antonio, USA  
Timothy Radstake, University Medical Center Utrecht, Netherlands 
Editorial Advisory Panel
Thomas Bieber, University of Bonn, Germany 
Michael Blaiss, University of Tennessee Health Science, USA 
Jean Bousquet, Montpellier University, France 
William Calhoun, University of Texas Medical Branch, TX, USA 
Giorgio Walter Canonica, Genoa University, Italy 
Kai-Håkon Carlsen, Oslo University Hospital , Norway 
Thomas Casale, Creighton University, USA 
Vinod Chandran, Toronto Western Hospital, Canada 
Mario Clerici, University of Milan, Italy 
Bonaventura Clotet, Hospital Universitari Germans Trias i Pujol, Spain 
Maripat Corr, University of California, USA 
Antonella Diamanti, Bambino Gesu Children Hospital, Italy 
Paul Emery, University of Leeds, UK 
Steven R. Feldman, Wake Forest University School of Medicine, USA 
Kenneth B. Gordon, Medical College of Wisconsin, USA 
Qutayba Hamid, McGill University, Canada 
Stephen B Hanauer, Northwestern University, USA 
Arthur Kavanaugh, University of California at San Diego, San Diego, USA 
Marek Kowalski, Medical University of Lodz, Poland 
Qianjin Lu, Central South University, Changsha, China 
Ronald T. Mitsuyasu, University of California, Los Angeles, USA  
John N. Nkengasong, Centers for Disease Control and Prevention, USA 
Luigi D. Notarangelo, Boston Children's Hospital, MA, USA 
Giuseppe Orlando, Wake Forest School of Medicine, NC, USA 
Kim A. Papp, Probity Medical Research, Canada 
Laurent Peyrin-Biroulet, University Hospital of Nancy-Brabois, France 
Nikolai Petrovsky, Flinders Medical Centre, Australia 
Nima Rezaei, Tehran University of Medical Sciences, Tehran, Iran 
Marc Rothenberg, Cincinnati Children's Hospital Medical Center, USA 
Carlo Salvarani, Ospedaliera ASMN, Italy 
Stanislaw Stepkowski, University of Toledo, USA 
Olaf Stuve, UTSouthwestern Medical Center, USA 
Anat R. Tambur, Feinberg School of Medicine, Northwestern University, USA 
Yoshiya Tanaka, University of Occupational & Environmental Health, Japan 
Matthias von Herrath, La Jolla Institute for Allergy and Immunology, USA 
Jeffrey M. Weinberg, Columbia University, NY, USA 
Dae Hyun Yoo, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea 
Luo Zhang, Capital Medical University, Beijing, China 
Yong Zhao, Chinese Academy of Sciences, China