李娟，PI，中科院杭州医学所研究员，博士生导师。国家优秀青年科学基金获得者。主要从事细胞膜蛋白功能分析和调控，肿瘤分子诊断和肿瘤免疫治疗的研究工作。

近年来，以通讯作者在国际高水平刊物上发表SCI论文60余篇，包括Science、J. Am. Chem. Soc.、 Angew. Chem. Int. Ed.，CCS Chemistry，Chem.Soc. Rev. 等。先后主持国家重点研发计划“合成生物学”专项课题、国家自然科学基金重大研究计划培养项目、优秀青年科学基金、国家自然科学基金青年项目等项目。申请中国发明专利9项，授权2项，PCT专利2项。多次在国际学术会议邀请做报告；担任BME Frontiers杂志副主编，美国化学会《Analytical Chemistry》杂志编辑顾问委员会委员、《肿瘤学杂志》中青年编委、《高等学校化学学报》《Chemical Research in Chinese Universities》青年执行编委。获中国化学会青年化学奖，省部级自然科学奖一等奖1项（第二完成人）。

10篇代表性论文：

1.      Zhentao Shao, Hui Yuan, Zhilan Zhou, Ya Wang, Peidong Hou, Hexin Nan, Wei Wang, Weihong Tan, and Juan Li*, Visualization of Protein-Specific Glycation in Living Cells via Bioorthogonal Chemical Reporter, Angew. Chem. Int. Ed., 2022, 10.1002/anie.202210069. (IF=16.823)

2.      Da Han, Juan Li*, Weihong Tan*, CRISPR propels a smart hydrogel, Science, 2019, 365(6455), 754-755. (IF=41.037)

3.      Da Zhang, Youshi Zheng, Ziguo Lin, Xiaolong Liu, Juan Li*, Huanghao Yang* and Weihong Tan, Equipping Natural Killer Cells with Specific Targeting and Checkpoint Blocking for Enhanced Adoptive Immunotherapy in Solid Tumors, Angew. Chem. Int. Ed. 2020, 59, 12022-12028. (IF=16.823)

4.      Kaiming Chen, Jie Zhou, Zhentao Shao, Jia Liu, Jia Song, Ruowen Wang*, Juan Li*, and Weihong Tan*, Aptamer as a Versatile Molecular Tool for Antibody Production Monitoring and Quality Control, J. Am. Chem. Soc., 2020, 142, 12079-12086 (IF=16.383)

5.      Shan Chen, Zhifei Xu, Wen Yang, Xiahui Lin, Jingying Li, Juan Li,* and Huanghao Yang, Logic-Gate-Actuated DNA-Controlled Receptor Assembly for the Programmable Modulation of Cellular Signal Transduction, Angew. Chem. Int. Ed., 2019, 58, 18186-18190. (IF=16.823)

6.      Long Li, Xigao Chen, Cheng Cui, Xiaoshu Pan, Xiaowei Li, Hoda Safari Yazd, Qiong Wu, Liping Qiu, Juan Li*, and Weihong Tan*, Aptamer displacement reaction from live-cell surfaces and its applications, J. Am. Chem. Soc., 2019, 141, 17174-17179. (IF=16.383)

7.      Liping Wang, Hong Liang, Jin Sun, Yichang Liu, Jinyu Li, Jingying Li, Juan Li*, Huanghao Yang*, Bispecific Aptamer Induced Artificial Protein-Pairing: A Strategy for Selective Inhibition of Receptor Function, J. Am. Chem. Soc. 2019, 141, 12673-12681. (IF=16.383)

8.      Jie Zhou, Liqin Sun, Liping Wang, Yichang Liu, Jinyu Li, Jingying Li, Juan Li,* and Huanghao Yang*, Self-Assembled and Size-Controllable Oligonucleotide Nanospheres for Effective Antisense Gene Delivery through an Endocytosis Independent Pathway, Angew. Chem. Int. Ed., 2019, 58, 5236-5240. (IF=16.823)

9.      Jingying Li, Shuya Liu, Liqin Sun, Wei Li, Su-Yun Zhang, Sheng Yang, Juan Li^*, and Huang-Hao Yang^*, Amplified Visualization of Protein-specific Glycosylation in Zebrafish via Proximity-induced Hybridization Chain Reaction, J. Am. Chem. Soc. 2018, 140, 16589-16595. (IF=16.383)

10.       Hong Liang, Shan Chen, Peipei Li, Liping Wang, Jingying Li, Juan Li*, Huang-Hao Yang* and Weihong Tan, Nongenetic approach for imaging protein dimerization by aptamer recognition and proximity-induced DNA assembly, J. Am. Chem. Soc., 2018, 140, 4186-4190. (IF=16.383)