Division of Organic Chemistry

Suzanne Walker: Harvard Medical School

Targeting O-GlcNAc Transferase

Andrew Myers: Harvard University

Discovery through chemical synthesis of Iboxamycin, an antibiotic effective against multidrug-resistant bacterial pathogens

Dale Boger: The Scripps Research Institute

Maxamycins: redesigned vancomycins for resistant bacteria

Lin Song: Cornell University

Electrochemistry: From cross-coupling to C–H functionalization

Phil Baran: The Scripps Research Institute

Electrochemical solutions to longstanding problems in synthesis

Division of Medicinal Chemistry

Guanglin Luo: Bristol Myers Squibb Co

Discoveryand Development of BMS-986176/LX-9211, a Highly Selective, Potent Oral andBrain Penetrable AAK1 Inhibitor for Neuropathic Pain

Mark Schnute: Pfizer Inc

Discovery of the CCR6 antagonist PF-07054894 for the treatment of autoimmune disorders

Deborah Mortensen: Bristol-Myers Squibb Co Research & Development

Discovery of CC-90001: A potent c-Jun N-terminal kinase (JNK) inhibitor for the treatment of fibrotic diseases

Severin Thompson: Revolution Medicines Inc

Discovery of a potent, selective, and orally bioavailable SOS1 inhibitor, RMC-0331, an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction

Margaret Chu-Moyer: Amgen

Philip S. Portoghese Medicinal Chemistry Senior Lectureship Award- Atom by atom: Inventing innovative medicines

Chao Fang: Arrakis Therapeutics

RNA targeting small molecules (rSM): An Arrakis approach

Elena Koltun: Revolution Medicines Inc

Discovery and development of allosteric inhibitors of SHP2

Donna Hayes: Merck & Co Inc

Lessons learned from small molecule tissue distribution studies accessing the back of the eye

Division of Biological Chemistry

Aaron Schmidt: Harvard Medical School

Eliciting protective antibodies targeting conserved viral epitopes by structure-guided immunogen

Pamela Bjorkman: California Institute of Technology

Neutralizing antibodies against coronaviruses

Lauren Rajakovich: Harvard University

Enzyme discovery completes the anaerobic pathway for gut microbial metabolism of l-carnitine linked to cardiovascular disease

Jennifer Petter: Arrakis Therapeutics

Drugging RNA: Building a broad discovery platform

Paul Thompson: University of Massachusetts Medical School

Citrullination: Inhibit, Identify, and Install