The effect of oxidative stress on muscle damage inducted by physical exercise is widely debated. It is generally agreed that endurance and intense exercise can increase oxidative stress and generate changes in antioxidant power inducing muscle damage; however, regular and moderate exercise can be beneficial for the health improving the antioxidant defense mechanisms in the majority of cases. Growing evidences suggest that an increased oxidative/nitrosative stress is involved in the pathogenesis of several muscular dystrophies (MDs). Notably, physical training has been considered useful for patients with these disorders. This review will focus on the involvement of oxidative stress in MDs and on the possible effects of physical activities to decrease oxidative damage and improve motor functions in MDs patients.

中文翻译：

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肌肉营养不良的体育锻炼和氧化应激：是否存在良好的平衡？

氧化应激对体育锻炼引起的肌肉损伤的作用受到广泛争议。人们普遍认为，耐力和剧烈运动会增加氧化应激并产生抗氧化能力的变化，从而导致肌肉损伤；但是，在大多数情况下，定期进行适度的运动可能有益于健康，改善抗氧化防御机制。越来越多的证据表明，氧化/亚硝化应激的增加与几种肌营养不良症（MDs）的发病机理有关。值得注意的是，体育锻炼已被认为对患有这些疾病的患者有用。这项审查将侧重于在MDs中的氧化应激的参与和体育活动对减少MDs患者的氧化损伤和改善运动功能的可能影响。