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Irreversible Electroporation: A Novel Ultrasound-guided Modality for Non-thermal Tumor Ablation.
Journal of Medical Ultrasound Pub Date : 2018-08-02 , DOI: 10.1016/j.jmu.2017.08.003
Chih-Yang Hsiao , Kai-Wen Huang

Ultrasound-guided tumor ablation techniques have been proven to be highly effective and minimally invasive in the treatment of many diseases. Traditional approaches to ablation include microwave and radiofrequency techniques, cryotherapy, and high-intensity focused ultrasound. However, these methods are prone to heat-sink effects that can diminish the effectiveness of treatment and damage adjacent structures, such as bile ducts, blood vessels, the gallbladder, or bowel. Irreversible electroporation (IRE) is a non-thermal ablation modality that induces cell apoptosis through the application of high-voltage current. IRE is not limited by many of the limitation which affects conventional tumor ablation techniques, and is particularly useful in treating sensitive areas of the body. The article reviews the basics of ultrasound-guided technology, including its clinical applications and effectiveness in the treatment of tumors.

中文翻译:

不可逆电穿孔:非热肿瘤消融的新型超声引导模式。

超声引导的肿瘤消融技术已被证明在许多疾病的治疗中是高效且微创的。消融的传统方法包括微波和射频技术,冷冻疗法以及高强度聚焦超声。但是,这些方法容易产生散热效果,从而降低治疗效果并损坏附近的结构,例如胆管,血管,胆囊或肠管。不可逆电穿孔(IRE)是一种非热消融方式,可通过施加高压电流来诱导细胞凋亡。IRE不受许多影响常规肿瘤消融技术的限制的限制,并且在治疗机体敏感区域时特别有用。本文回顾了超声引导技术的基础知识,
更新日期:2019-11-01
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