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The cardiovascular health score and the volume of carotid body in computed tomography angiography in patients with arterial hypertension.
Journal of the American Society of Hypertension Pub Date : 2018-05-23 , DOI: 10.1016/j.jash.2018.04.006
Przemysław Jaźwiec 1 , Paweł Gać 2 , Małgorzata Poręba 3 , Małgorzata Sobieszczańska 3 , Grzegorz Mazur 4 , Rafał Poręba 4
Affiliation  

The cardiovascular health (CVH) score constitutes a reliable and measurable indicator of CVH proposed by the American Heart Association (AHA) calculated based on seven fundamental parameters, that is, smoking, body mass index, physical activity, healthy diet score, blood pressure, blood cholesterol, and fasting plasma glucose. The size and activity of carotid body (CB) play an important role in the pathogenesis of the cardiovascular system. The objective of this study was to define the relationship between the AHA CVH score and the volume of CB (VrCB+lCB) estimated based on computed tomography angiography (CTA) in patients with arterial hypertension. Studies were conducted on a group of 57 patients with arterial hypertension (age: 70.74 ± 8.21 years). The CVH score was calculated, and CTA of carotid arteries was carried out for all patients. The CB analysis was performed based on delayed phase imaging obtained from CTA of carotid arteries. Based on the CVH score value, CVH was determined as optimal (CVH score between 10 and 14 points), average (5 and 9 points), or inadequate (0 and 4 points). CVH score in the studied group of patients was 6.53 ± 1.81, whereas VrCB+lCB value was 38.58 ± 18.43 mm3. Patients with an inadequate CVH score (0-4 points) have statistically significantly higher VrCB+lCB, and they are fraught with VrCB+lCB ≥ median much more often than patients with an optimal CVH score (10-14 points). The receiver operating characteristic curve indicated a CVH score value of 6 as an optimal cutoff point to predict VrCB+lCB ≥ median. The CVH score ≤6 criterion indicates VrCB+lCB ≥ median with sensitivity of 58.6% and specificity of 71.4%. In the regression analysis, it was indicated that lower partial scores for physical activity, healthy diet score, and blood pressure in the AHA CVH evaluation constitute independent risk factors for higher VrCB+lCB. In the studied group of patients with arterial hypertension, an inversely proportional dependence between the CVH score and the size of CB is observed in CTA of carotid arteries.

中文翻译:

动脉高压患者的计算机断层造影血管造影中的心血管健康评分和颈动脉体积。

心血管健康(CVH)评分构成了美国心脏协会(AHA)提出的可靠且可测量的CVH指标,该指标是根据七个基本参数计算得出的,这些基本参数是吸烟,体重指数,身体活动,健康饮食评分,血压,血液中的胆固醇,以及空腹血糖。颈动脉体(CB)的大小和活性在心血管系统的发病机理中起着重要作用。这项研究的目的是要确定AHA CVH评分与基于计算机断层造影血管造影(CTA)估计的高血压患者CB量(VrCB + 1CB)之间的关系。研究针对一组57位动脉高血压患者(年龄:70.74±8.21岁)进行。计算所有患者的CVH评分,并进行颈动脉CTA。基于从颈动脉CTA获得的延迟相成像进行CB分析。根据CVH得分值,将CVH确定为最佳(CVH得分在10到14分之间),平均(5到9分)或不足(0到4分)。研究组患者的CVH评分为6.53±1.81,而VrCB + 1CB值为38.58±18.43 mm3。CVH分数不足(0-4分)的患者具有统计学上显着更高的VrCB + 1CB,并且与最佳CVH分数(10-14分)相比,他们对VrCB + 1CB≥中位数的困扰更为频繁。接收器工作特性曲线表明CVH得分值为6,这是预测VrCB + ICB≥中位数的最佳截止点。CVH分数≤6的标准表示VrCB + 1LCB≥中位数,敏感性为58.6%,特异性为71.4%。在回归分析中 研究表明,AHA CVH评估中较低的身体活动分数,健康饮食分数和血压构成较高VrCB + 1CB的独立危险因素。在研究组的动脉高血压患者中,在颈动脉的CTA中观察到CVH评分与CB大小成反比关系。
更新日期:2019-11-01
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