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Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review
Gastrointestinal Tumors Pub Date : 2020-08-18 , DOI: 10.1159/000509186
Andreas Mavroudis , Evangelos Cholongitas

Hepatocellular carcinoma (HCC) is considered to be the fourth most frequent cause of cancer-associated death globally. HCC might be associated, especially in advanced stages, with the formation of tumor thrombus (TT), which can be located in the portal vein, as well as in hepatic and/or inferior vena cava (IVC) veins. Nevertheless, the extension of TT to the right atrium (RA) is infrequent with an unfavorable prognosis. We present a rare case of a male patient with HCC and IVC TT extending to the RA. The atrial thrombus was the first manifestation of HCC diagnosed by cardiac ultrasound. So far, the patient has undergone 4 courses of transarterial chemoembolization in combination with systemic therapy with sorafenib, and under this therapeutic approach long-term survival has been achieved.
Gastrointest Tumors


中文翻译:

肝细胞癌和肿瘤性房血栓患者在动脉化疗栓塞和索拉非尼下的长期生存:病例报告和文献复习

肝细胞癌(HCC)被认为是全球癌症相关死亡的第四大最常见原因。HCC可能与肿瘤血栓(TT)的形成有关,尤其是在晚期阶段,它可以位于门静脉以及肝和/或下腔静脉(IVC)静脉中。然而,TT很少扩展到右心房(RA),预后不良。我们介绍了HCC和IVC TT延伸至RA的男性患者的罕见病例。心房血栓是通过心脏超声诊断出的HCC的首例表现。迄今为止,该患者已经接受了4个疗程的经动脉化学栓塞治疗,并与索拉非尼进行全身治疗相结合,并且在这种治疗方法下已经实现了长期生存。
胃肠道肿瘤
更新日期:2020-08-18
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