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An Efficient Selectfluor-Mediated Oxidative Thio- and Selenocyanation of Diversely Substituted Indoles and Carbazoles
Heteroatom Chemistry ( IF 0.3 ) Pub Date : 2019-01-02 , DOI: 10.1155/2019/1459681
Rodrigo Abonia 1 , Luisa F. Gutierrez 1, 2 , Angela T. Zwarycz 2 , Sebastián Correa Smits 2 , Kenneth K. Laali 2
Affiliation  

A facile Selectfluor-mediated oxidative method for direct introduction of SCN and SeCN groups into diversely substituted indoles and carbazoles is described, by employing readily available thiocyanate and selenocyanate salts, and the scope of the method is underscored by providing 24 examples. The feasibility to sequentially introduce SCN followed by SeCN on a carbazole framework and to synthesize the corresponding S-tetrazole and Se-tetrazole derivatives is also demonstrated.

中文翻译:

多种取代的吲哚和咔唑的高效 Selectfluor 介导的氧化硫代和硒代氰化

描述了一种简便的 Selectfluor 介导的氧化方法,用于将 SCN 和 SeCN 基团直接引入不同取代的吲哚和咔唑中,通过使用容易获得的硫氰酸盐和硒氰酸盐,并通过提供 24 个例子强调了该方法的范围。还证明了在咔唑框架上依次引入 SCN 和 SeCN 并合成相应的 S-四唑和 Se-四唑衍生物的可行性。
更新日期:2019-01-02
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