Abstract

Flavonoids and lignin are valuable phytochemicals derived from plant secondary metabolism and play important roles in regulating multiple plant developmental processes and signaling networks. The biosynthetic pathways leading to flavonoids and lignin are known to be originated from the general phenylpropanoid pathway. Key regulators controlling the pathway structural genes have been isolated from many species. However, cooperative regulations of flavonoid and lignin biosynthesis and the resulting effects on the carbon flow in the general phenylpropanoid pathway have not systematically summarized and discussed. New discoveries have begun to reveal that the biosynthesis of flavonoids and lignin are linked through transcription regulatory networks sharing certain specific regulators, such as transcription factors, mediators and microRNAs. This review article summarizes recent progress on function and mechanism of these regulators and assesses how they co-modulate the biosynthesis of flavonoids and lignin. A simplified discussion for the different co-regulation networks involved with flavonoid and lignin biosynthesis is proposed.

摘要

类黄酮和木质素是源自植物次生代谢的有价值的植物化学物质，在调节多种植物发育过程和信号网络中起重要作用。已知导致类黄酮和木质素的生物合成途径起源于一般的苯丙烷途径。已经从许多物种中分离出了控制途径结构基因的关键调控因子。然而，尚未系统地总结和讨论黄酮和木质素生物合成的合作规定以及由此产生的对一般苯丙烷途径中碳流量的影响。新发现已开始揭示类黄酮和木质素的生物合成是通过共享某些特定调节剂（例如转录因子，介体和microRNA）的转录调节网络联系在一起的。这篇综述文章总结了这些调节剂在功能和机理上的最新进展，并评估了它们如何共同调节类黄酮和木质素的生物合成。提出了涉及类黄酮和木质素生物合成的不同共调节网络的简化讨论。