Annual Review of Vision Science ( IF 6 ) Pub Date : 2021-09-15 , DOI: 10.1146/annurev-vision-100419-115156 James B Hurley 1
The outer retina is nourished from the choroid, a capillary bed just inside the sclera. O2, glucose, and other nutrients diffuse out of the choroid and then filter through a monolayer of retinal pigment epithelium (RPE) cells to fuel the retina. Recent studies of energy metabolism have revealed striking differences between retinas and RPE cells in the ways that they extract energy from fuels. The purpose of this review is to suggest and evaluate the hypothesis that the retina and RPE have complementary metabolic roles that make them depend on each other for survival and for their abilities to perform essential and specialized functions.
中文翻译：
色素上皮中的视网膜代谢和代谢：繁忙的交叉点
外层视网膜由脉络膜滋养，脉络膜是巩膜内的毛细血管床。O 2、葡萄糖和其他营养物质从脉络膜中扩散出来，然后通过单层视网膜色素上皮 (RPE) 细胞过滤，为视网膜提供能量。最近对能量代谢的研究揭示了视网膜和 RPE 细胞在从燃料中提取能量的方式上存在显着差异。这篇综述的目的是提出和评估视网膜和 RPE 具有互补的代谢作用的假设，这使得它们在生存和执行基本和特殊功能的能力方面相互依赖。
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