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A bending fluctuation-based mechanism for particle detection by ciliated structures [Physics]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2021-08-03 , DOI: 10.1073/pnas.2020402118
Jean-Baptiste Thomazo 1, 2 , Benjamin Le Révérend 3 , Lea-Laetitia Pontani 1 , Alexis M Prevost 4 , Elie Wandersman 4
Affiliation  

To mimic the mechanical response of passive biological cilia in complex fluids, we study the bending dynamics of an anchored elastic fiber submitted to a dilute granular suspension under shear. We show that the bending fluctuations of the fiber accurately encode minute variations of the granular suspension concentration. Indeed, besides the stationary bending induced by the continuous phase flow, the passage of each single particle induces an additional deflection. We demonstrate that the dominant particle/fiber interaction arises from contacts of the particles with the fiber, and we propose a simple elastohydrodynamics model to predict their amplitude. Our results provide a mechanistic and statistical framework to describe particle detection by biological ciliated systems.



中文翻译:

基于弯曲波动的纤毛结构粒子检测机制 [物理学]

为了模拟被动生物纤毛在复杂流体中的机械响应,我们研究了锚定弹性纤维在剪切下经受稀颗粒悬浮液的弯曲动力学。我们表明,纤维的弯曲波动准确地编码了颗粒悬浮液浓度的微小变化。实际上,除了由连续相流引起的静止弯曲外,每个单个粒子的通过都会引起额外的偏转。我们证明了主要的粒子/纤维相互作用是由粒子与纤维的接触引起的,我们提出了一个简单的弹性流体动力学模型来预测它们的振幅。我们的结果提供了一个机械和统计框架来描述生物纤毛系统的粒子检测。

更新日期:2021-07-30
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