Salicylaldehyde derived hexadentate Schiff base N,N‟-Bis[2-salicylideneamino]ethane-1,2-diamine (TTS) and its complexes with Fe(III), Co(II) and Cu(II) metal ions have been prepared and characterised by elemental analysis, UV-visible, IR, 1H NMR, EPR spectral analysis, mass spectrometry and XRD method. In vitro antibacterial activity of the Schiff base and its metal complexes against Gram positive bacterial strains Staphylococus aureus, Bacillus subtilis and Gram negative bacterial strains Enterobacter, Escherichia coli has revealed that the metal complexes are more active to the bacterial strains as compared to that of the Schiff base. The Co-TTS has the highest antibacterial activity against Escherichia coli, while the Fe-TTS complex is highly active against Enterobacter, Staphylococcus aureus and Bacillus subtilis.

中文翻译：

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N,N'-Bis[2-salicylideneamino]ethane-1,2-diamine 的 Fe(III)、Co(II) 和 Cu(II) 配合物：制备、表征和体外抗菌活性

已制备出水杨醛衍生的六齿席夫碱 N,N'-双[2-水杨基氨基]乙烷-1,2-二胺 (TTS) 及其与 Fe(III)、Co(II) 和 Cu(II) 金属离子的络合物，并通过元素分析、紫外-可见光、红外、1H NMR、EPR光谱分析、质谱和XRD方法对其进行表征。席夫碱及其金属配合物对革兰氏阳性菌金黄色葡萄球菌、枯草芽孢杆菌和革兰氏阴性菌肠杆菌、大肠杆菌的体外抗菌活性表明，与大肠杆菌相比，金属配合物对细菌菌株的活性更高席夫碱。Co-TTS 对大肠杆菌的抗菌活性最高，而 Fe-TTS 复合物对肠杆菌、金黄色葡萄球菌和枯草芽孢杆菌的抗菌活性很高。