The term host defense peptides arose at the beginning to refer to those peptides that are part of the host’s immunity. Because of their broad antimicrobial capacity and immunomodulatory activity, nowadays, they emerge as a hope to combat resistant multi-drug microorganisms and emerging viruses, such as the case of coronaviruses. Since the beginning of this century, coronaviruses have been part of different outbreaks and a pandemic, and they will be surely part of the next pandemics, this review analyses whether these peptides and their derivatives are ready to be part of the treatment of the next coronavirus pandemic.

中文翻译：

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宿主防御肽及其衍生物是否准备好成为下一次冠状病毒大流行治疗的一部分？

宿主防御肽一词最初是指作为宿主免疫一部分的肽。由于它们广泛的抗菌能力和免疫调节活性，如今，它们成为对抗耐药性多药微生物和新兴病毒（例如冠状病毒）的希望。自本世纪初以来，冠状病毒已成为不同爆发和大流行的一部分，并且它们肯定会成为下一次大流行的一部分，本综述分析了这些肽及其衍生物是否已准备好成为下一次冠状病毒治疗的一部分大流行病。