Chalcones, (E)-N-(4-(4,6-dichloro-1,3,5 –triazin-2-ylamino) phenyl)-3-(4 methoxy-phenyl) acrylamide 4a-c have been prepared by employing Claisen-Schmidt condensation. Further, these chalcones 4a-c on reaction with malononitrile afford cyano-pyridines 5a-c respectively. The constitution of newly synthesised compounds have been characterized on the basis of their IR, ¹H and ¹³C NMR spectral data. These synthesized compounds have been screened for their antibacterial and larvicidal activity.

中文翻译：

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一些新型查耳酮及其衍生物的生物学评价

查耳酮，(E)-N-(4-(4,6-dichloro-1,3,5-triazin-2-ylamino) 苯基)-3-(4 甲氧基-苯基)丙烯酰胺 4a-c 已通过使用制备克莱森-施密特凝聚。此外，这些查耳酮 4a-c 与丙二腈反应分别得到氰基吡啶 5a-c。新合成化合物的组成已根据其 IR、¹ H 和¹³ C NMR 光谱数据进行表征。已经筛选了这些合成化合物的抗菌和杀幼虫活性。