当前位置: X-MOL 学术Adv. Model. and Simul. in Eng. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Coupling reduced-order blood flow and cardiac models through energy-consistent strategies: modeling and discretization
Advanced Modeling and Simulation in Engineering Sciences Pub Date : 2021-09-28 , DOI: 10.1186/s40323-021-00206-4
Jessica Manganotti 1, 2 , Federica Caforio 1, 2, 3 , François Kimmig 1, 2 , Philippe Moireau 1, 2 , Sebastien Imperiale 1, 2
Affiliation  

In this work we provide a novel energy-consistent formulation for the classical 1D formulation of blood flow in an arterial segment. The resulting reformulation is shown to be suitable for the coupling with a lumped (0D) model of the heart that incorporates a reduced formulation of the actin-myosin interaction. The coupling being consistent with energy balances, we provide a complete heart-circulation model compatible with thermodynamics hence stable numerically and informative physiologically. These latter two properties are verified by numerical experiments.

中文翻译:

通过能量一致策略耦合降阶血流和心脏模型:建模和离散化

在这项工作中,我们为动脉段血流的经典一维公式提供了一种新的能量一致公式。结果表明,所得的重新制定适用于与心脏的集总 (0D) 模型耦合,该模型结合了肌动蛋白-肌球蛋白相互作用的简化公式。这种耦合与能量平衡一致,我们提供了一个与热力学兼容的完整心脏循环模型,因此在数值和生理信息上是稳定的。后两种性质通过数值实验得到验证。
更新日期:2021-09-29
down
wechat
bug