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Ultrasound mediated synthesis of aldimines from non-enolizable aldehydes at room temperature
Indian Journal of Chemistry, Section B ( IF 0.456 ) Pub Date : 2021-12-15
Dipankar Paula, Gitumoni Kalitaa, Hridoy Jyoti Boraa, Suman Samaib, Paresh Nath Chatterjee

user-friendly, energy efficient method of synthesizing N-sulfonyl aldimines at room temperature (25‒28°C) from readily available and inexpensive reagents has been developed. The method employs ultrasonication from common laboratory ultrasonic cleaner to mediate the reaction. FeCl3 as catalyst and molecular sieves as water scavenger have produced excellent yields of aldimines with short reaction time. The reaction set-up does not require inert atmosphere or anhydrous solvent thereby saving resources and time. The easily scalable method works well for the condensation of aromatic non-enolizable aldehydes and sulfonamides.

中文翻译:

在室温下由非烯醇化醛超声介导合成醛亚胺

已经开发出一种用户友好、节能的方法,可在室温 (25-28°C) 下从易得且廉价的试剂合成 N-磺酰醛亚胺。该方法使用来自普通实验室超声波清洗器的超声波处理来介导反应。FeCl3 作为催化剂,分子筛作为除水剂,在较短的反应时间内产生了极好的醛亚胺收率。反应装置不需要惰性气氛或无水溶剂,从而节省资源和时间。这种易于扩展的方法非常适用于芳香族非烯醇化醛和磺酰胺的缩合。
更新日期:2021-12-15
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