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Application value of Co(II) coordination polymer in the treatment and operational nursing of hypothermia
Indian Journal of Chemistry, Section A ( IF 0.412 ) Pub Date : 2021-12-16
Sha Li, Ye Li, Fang-Yu Zhou

A novel coordination polymer, [Co3(OABDC)2(bipy)3 (H2O)6]n(CH3OH)n(H2O)4.5n (1), has been synthesised by hydrothermal method with the coordination of 4,4′-bipy ligand and 3,5-dicarboxyphenoxyacetic acid (H3OABDC) to cobalt(II) ions. The treatment and nursing application values of 1 on hypothermia in patients undergoing surgery has been examined, and the specific mechanism is explored. The application of the compound on the body temperature is measured with an in vitro infrared thermometer. Then, the relative expression of vascular α-receptors is determined by real-time RT-PCR. The toxicity and biocompatibility of the new compound is also determined.

中文翻译:

Co(II)配位聚合物在低温治疗及手术护理中的应用价值

一种新型配位聚合物,[Co3(OABDC)2(bipy)3 (H2O)6]n(CH3OH)n(H2O)4.5n (1),已通过水热法与 4,4'-bipy 配位合成配体和 3,5-二羧基苯氧基乙酸 (H3OABDC) 生成钴 (II) 离子。探讨了1对手术患者体温过低的治疗及护理应用价值,探讨了具体机制。用体外红外测温仪测量化合物对体温的应用。然后,通过实时 RT-PCR 确定血管 α 受体的相对表达。还确定了新化合物的毒性和生物相容性。
更新日期:2021-12-16
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