ABSTRACT

Objective: To examine associations between sleep-disordered breathing (SDB) and executive/attentional function in pediatric sickle cell disease (SCD). Methods: Sixty youth with SCD ages 8–18 years and caregivers completed the Pediatric Sleep Questionnaire (PSQ), Delis Kaplan Executive Function System Trail Making Test (DKEFS TMT), Psychomotor Vigilance Test (PVT), and the Behavior Rating Inventory Of Executive Function, Second Edition (BRIEF-2) Parent Report. Results: The PSQ significantly predicted the BRIEF-2 Parent Report, F(1, 58) = 44.64, p < .001, R² = 0.44, f² = 0.77. Conclusions: Sleep-disordered breathing symptoms may predict informant-rated executive dysfunction in pediatric SCD, but not performance-based executive function.

摘要

目的：研究儿童镰状细胞病 (SCD) 中睡眠呼吸障碍 (SDB) 与执行/注意功能之间的关联。方法：60 名 8-18 岁 SCD 青少年和护理人员完成了儿科睡眠问卷 (PSQ)、Delis Kaplan 执行功能系统跟踪测试 (DKEFS TMT)、精神运动警觉性测试 (PVT) 和执行功能行为评定量表, 第二版 (BRIEF-2) 家长报告。结果：PSQ 显着预测了 Brief-2 父报告，F (1, 58) = 44.64, p < .001, R ²  = 0.44, f ² = 0.77。结论：睡眠呼吸障碍症状可以预测儿童 SCD 的知情人执行功能障碍，但不能预测基于表现的执行功能。