Background: An infant air-jet dry powder inhaler (DPI) platform has recently been developed that in combination with highly dispersible spray-dried powder formulations can achieve high-efficiency aerosolization with low actuation air volumes. The objective of this study was to investigate modifications to the nasal interface section of this platform to improve the aerosol delivery performance through preterm nose–throat (NT) models.

中文翻译：

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早产儿高效气雾剂鼻腔接口选项的体外分析

背景：最近开发了一种婴儿喷气干粉吸入器（DPI）平台，与高度分散的喷雾干粉制剂相结合，可以以低驱动空气量实现高效雾化。本研究的目的是研究对该平台鼻界面部分的修改，以通过早产鼻咽 (NT) 模型改善气雾剂输送性能。