Background: 

The Attention Network Test (ANT) is a well-established measure of efficiency for the alerting, orienting, and executive attentional networks. However, its novel application in Parkinson disease (PD) and Lewy body dementia (LBD) research more broadly has yet to be evaluated systematically.

Objective: 

To compare and consolidate the outcomes of studies reporting use of the ANT in PD and LBD groups and to identify the methodological considerations for the conduct of such studies.

Method: 

We performed a systematic literature search for articles exploring attention in PD and LBD groups using the ANT. We excluded articles on the basis of irrelevant scope, non-English, and groups other than PD and LBD. Once the full text articles were identified, we extracted the data and assessed the studies’ quality.

Results: 

The final sample included 16 articles ranging from low to moderate quality. Behavioral findings suggested a general slowing of responses yet preserved accuracy from the PD group compared with controls. Overall, the evidence was inconclusive regarding the state of the alerting network in the PD and LBD groups, mostly supportive of an intact orienting network, and strongly suggestive of an impaired executive network. Differences in sample stratification, patient symptomatology, and dopaminergic medication levels were identified as influential factors in the attentional results across studies.

Conclusion: 

Although sparse, the existing evidence indicates that the ANT is a viable option for measuring attention in PD; it can also be harnessed to explore the impact of symptoms and medications on attentional networks in PD and LBD groups.

中文翻译：

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帕金森和路易体病的注意力网络测试：系统评价

背景： 

注意力网络测试 (ANT) 是一种行之有效的衡量警报、定向和执行注意力网络效率的方法。然而，其在帕金森病 (PD) 和路易体痴呆 (LBD) 研究中的新应用尚未得到系统评估。

客观的： 

比较和综合报告在 PD 和 LBD 组中使用 ANT 的研究结果，并确定进行此类研究的方法学考虑因素。

方法： 

我们使用 ANT 对探索 PD 和 LBD 组注意力的文章进行了系统的文献检索。我们根据不相关的范围、非英语以及 PD 和 LBD 以外的组排除了文章。一旦确定了全文文章，我们就会提取数据并评估研究的质量。

结果： 

最终样本包括 16 篇从低质量到中等质量的文章。行为研究结果表明，与对照组相比，PD 组的反应普遍放缓，但仍保持准确性。总体而言，关于 PD 和 LBD 组警报网络状态的证据尚无定论，主要支持完整的定向网络，并强烈暗示执行网络受损。样本分层、患者症状和多巴胺能药物水平的差异被确定为研究中注意力结果的影响因素。

结论： 

虽然稀少，但现有证据表明 ANT 是衡量 PD 注意力的可行选择；它还可以用于探索症状和药物对 PD 和 LBD 组注意力网络的影响。