Genetic factors contribute to the development of anxiety disorders, yet few risk genes have been previously identified. One genomic approach that has achieved success in identifying risk genes in related childhood neuropsychiatric conditions is investigations of de novo variants, which has yet to be leveraged in childhood anxiety disorders.

中文翻译：

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儿童焦虑症的全外显子组 DNA 测序识别出罕见的新生破坏性编码变体

遗传因素会导致焦虑症的发展，但之前发现的风险基因很少。在识别相关儿童神经精神疾病的风险基因方面取得成功的一种基因组方法是对从头变异的研究，该方法尚未用于儿童焦虑症。