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Development and characterization of gelatin-based herbal hydrogels for managing infected wounds
Indian Journal of Fibre & Textile Research ( IF 0.6 ) Pub Date : 2022-03-24
Kanagaraj Suganya, Dhandapani Kavitha, Elango Santhini

The present study is aimed at evaluating the antioxidant and antimicrobial properties of aqueous extracts of the plants Moringa olifera (drumstick tree or murungai), Sesbania grandiflora (vegetable hummingbird or agati), Basella alba (malabar spinach or pasalai), and then developing herbal hydrogel with gelatin to improve its pharmacological properties and to use it as a primary dressing for managing infected wounds. The aqueous extracts of murungai, agati, pasalai and the herbal hydrogels has been tested in vitro against wound infecting microrganisms by well-diffusion method and micro-dilution method. Both plant extracts and herbal hydrogel are found to inhibit the growth of Gram positive, Gram negative and polymicrobial cultures. According to EN13726, all the three herbal hydrogels manage the simulated exudates effectively. Hence, the hydrogels developed in the present study could be used to manage infection and also moderately exudating wounds.

中文翻译:

用于治疗感染伤口的基于明胶的草药水凝胶的开发和表征

本研究旨在评估植物辣木(鼓槌树或 murungai)、田菁(植物蜂鸟或 agati)、Basella alba(马拉巴尔菠菜或 pasalai)的水提取物的抗氧化和抗菌特性,然后开发草药水凝胶与明胶一起改善其药理特性,并将其用作治疗感染伤口的主要敷料。murungai、agati、pasalai 和草本水凝胶的水提取物已通过充分扩散法和微量稀释法在体外对感染伤口的微生物进行了测试。发现植物提取物和草药水凝胶均能抑制革兰氏阳性、革兰氏阴性和多种微生物培养物的生长。根据 EN13726,所有三种草本水凝胶都能有效管理模拟渗出液。因此,
更新日期:2022-03-24
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