Abstract

Objective

Evidence from real-world integrated dual diagnosis treatment programs is limited. In 2017 we decided to establish the REDD-PAC cohort with the aim to provide more in-depth information regarding the effect of integrated treatment.

Methods

The REDD-PAC cohort includes more than 2,500 patients with dual diagnosis that have been treated at an in-patient department specializing in the integrated treatment of both psychiatric illness and substance use disorder in Denmark in the period from 2002 to 2017. The collected data included information on diagnosis as well as patient-completed questionnaires regarding anxiety, depression, self-worth, and use of substances. Data regarding medications prescribed and administered, weight, height, and blood pressure were also included.

Results

The primary diagnosis was psychosis spectrum disorder (37.0%), followed by affective disorders (18.8%). More than two-thirds of the patients were male, and most patients had a weak connection to the labor market and basic schooling. Patients were generally very motivated for treatment.

Conclusions

Further linking the data to Danish national register data makes it possible to follow individual trajectories pre- and post-admission as well as to access complete follow-up data regarding long-term outcomes, e.g., use of health services, mortality, morbidity, crime, and social circumstances. This article describes both the overarching aims of the REDD-PAC cohort and the basic diagnostic and sociodemographic characteristics of the cohort.

中文翻译：

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REDD-PAC 队列描述：研究双重诊断——预后和特征

摘要

客观的

来自现实世界综合双重诊断治疗方案的证据有限。2017 年，我们决定建立 REDD-PAC 队列，旨在提供有关综合治疗效果的更深入信息。

方法

REDD-PAC 队列包括 2,500 多名双重诊断患者，这些患者在 2002 年至 2017 年期间在丹麦专门从事精神疾病和物质使用障碍综合治疗的住院部门接受治疗。收集的数据包括诊断信息以及患者完成的关于焦虑、抑郁、自我价值和物质使用的问卷。还包括有关处方和给药的药物、体重、身高和血压的数据。

结果

主要诊断为精神病谱系障碍（37.0%），其次是情感障碍（18.8%）。超过三分之二的患者是男性，大多数患者与劳动力市场和基础教育的联系较弱。患者通常非常积极地进行治疗。

结论

进一步将数据与丹麦国家登记数据联系起来，可以跟踪入院前和入院后的个人轨迹，并获得有关长期结果的完整后续数据，例如，使用卫生服务、死亡率、发病率、犯罪, 和社会环境。本文描述了 REDD-PAC 队列的总体目标以及队列的基本诊断和社会人口学特征。