ABSTRACT

Two service members were diagnosed with PTSD due to military trauma exposure. One presented with the classical manifestation; the other presented with the dissociative subtype. A statistical map revealed anterior localization of insula connectivity in the classical PTSD patient and posterior localization in the dissociative PTSD patient. These differences suggest that dissociative PTSD may be identified, understood, and treated as a disorder related to increased posterior insula connectivity. This double case study provides preliminary evidence for a concrete neuroanatomical discrepancy between insula function in classical and dissociative PTSD that may help explain the emergence of different coping strategies.

摘要

由于军事创伤暴露，两名服役人员被诊断出患有创伤后应激障碍。一种以古典表现形式呈现；另一个呈现分离亚型。统计图显示经典 PTSD 患者的岛叶连通性的前部定位和分离性 PTSD 患者的后部定位。这些差异表明分离性 PTSD 可以被识别、理解和治疗为与后岛叶连接性增加相关的疾病。这个双重案例研究为经典和解离性 PTSD 中岛叶功能之间的具体神经解剖学差异提供了初步证据，这可能有助于解释不同应对策略的出现。