ABSTRACT

The evidence of hyperparathyroidism associated with cerebral calcifications is rare. We report a case with primary hyperparathyroidism (PHPT) and cerebral calcifications. A 63-year-old female patient with a history of hypertension presented to the neurology department due to bradykinesia and declining memory for one year. Cranial CT and magnetic resonance imaging (MRI) scan revealed symmetrical calcifications in the basal ganglia, dentate nucleus of the cerebellum and in the gray and white matter junction. In the literature review, a total of 6 patients with PHPT had cerebral calcifications. Parathyroidectomy may provide a significant remission of cerebral calcifications in a patient with PHPT.

摘要

与脑钙化相关的甲状旁腺功能亢进症的证据很少见。我们报告一例原发性甲状旁腺功能亢进 (PHPT) 和脑钙化。一名有高血压病史的 63 岁女性患者因运动迟缓和记忆力下降 1 年到神经内科就诊。头颅 CT 和磁共振成像 (MRI) 扫描显示基底节、小脑齿状核和灰白质交界处对称钙化。在文献回顾中，共有 6 例 PHPT 患者出现脑钙化。甲状旁腺切除术可以显着缓解 PHPT 患者的脑钙化。