Background and aims: Drug-related death (DRD) is a major public health concern in the Nordic countries, in the rest of Europe and in the US. After a DRD, approximately 10–15 next of kin will be left behind. People bereaved after sudden and unexpected deaths have a documented higher risk of reduced quality of life, daily functioning, and early death. It is important to know the resources professional helpers have available to them, the barriers and possibilities they face in their work, and how they can respond to the needs of the bereaved. This knowledge can help prevent severe health and social consequences of bereavement following a DRD. In this systematic review, the aim was to explore knowledge regarding professional helpers’ experiences of providing assistance to people bereaved after a DRD. Methods: Inclusion criteria were empirical studies of professional helpers’ first-person perspectives on meeting the bereaved after a DRD. Quantitative, qualitative, and mixed-method studies were included. Results: The results show that there are no studies addressing professional helpers’ experiences of providing assistance to the bereaved after a DRD. Conclusion: There is a vital need to develop more knowledge of professional helpers’ perspectives. This knowledge is important not only to improve education and the quality of health and social services, but also to help raise awareness of the bereaved after a DRD.

背景和目的：药物相关死亡 (DRD) 是北欧国家、欧洲其他国家和美国的主要公共卫生问题。在 DRD 之后，将留下大约 10-15 个近亲。突然和意外死亡后失去亲人的人有更高的生活质量、日常功能和早逝风险。重要的是要了解专业助手可以使用的资源、他们在工作中面临的障碍和可能性，以及他们如何应对丧亲者的需求。这些知识可以帮助预防 DRD 后丧亲带来的严重健康和社会后果。在这项系统评价中，目的是探索有关专业助手为 DRD 后失去亲人的人提供帮助的经验的知识。方法：纳入标准是对专业助手在满足 DRD 后失去亲人的第一人称视角的实证研究。包括定量、定性和混合方法研究。结果：结果表明，没有研究涉及专业助手在 DRD 后为失去亲人提供帮助的经历。结论：迫切需要更多地了解专业助手的观点。这些知识不仅对改善教育和健康和社会服务质量很重要，而且有助于提高对 DRD 后失去亲人的认识。