ABSTRACT

The purpose of this single subject study was to investigate whether transcranial direct current stimulation (tDCS) applied to both hemispheres combined with speech therapy can improve language learning in a pair of 5-year-old twins with corpus callosum dysgenesis (CCD). The treatment protocol included anodal tDCS with simultaneous speech therapy in one of the participants (T.D.), and sham-tDCS with the same montage, and stimulation regime concomitant with speech therapy for the other twin (A.D.). Our findings show that T.D. improved in language production when treated with speech therapy in combination with tDCS. A.D. showed evidence for a relatively minor behavioral benefit from speech therapy.

摘要

这项单一主题研究的目的是调查应用于双侧大脑半球的经颅直流电刺激 (tDCS) 与言语治疗相结合是否可以改善一对患有胼胝体发育不全 (CCD) 的 5 岁双胞胎的语言学习。治疗方案包括对其中一名参与者 (TD) 进行同步言语治疗的阳极 tDCS，以及对另一名双胞胎 (AD) 进行相同蒙太奇的假 tDCS，以及伴随言语治疗的刺激方案。我们的研究结果表明，当语言治疗与 tDCS 联合治疗时，TD 在语言生成方面得到了改善。AD 显示语言治疗对行为的益处相对较小。