Ursolic acid inhibits Th17 cell differentiation via STAT3/RORγt pathway and suppresses Schwann cell-mediated Th17 cell migration by reducing CXCL9/10 expression,Innate Immunity

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Ursolic acid inhibits Th17 cell differentiation via STAT3/RORγt pathway and suppresses Schwann cell-mediated Th17 cell migration by reducing CXCL9/10 expression
Innate Immunity ( IF 3.2 ) Pub Date : 2022-05-12 , DOI: 10.1177/17534259221094559
Hua Xu _{1,

2} , Ai-Ling Yu ₂ , Da-Peng Zhao ₂ , Guang-Yuan Meng ₃ , Ling Wang ₄ , Min Shan ₂ , Nai-Xia Hu ₂ , Yun-Lin Liu ₂

Affiliation

Th17 cells represent important immune cells. Ursolic acid (UA) can regulate immune cell activities. This study was aimed to explore the effects of UA on Th17 cell differentiation and Schwann cell(S...

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