ABSTRACT

Tallman and colleagues (this issue) showed that memory consolidation of laboratory materials produces, even at short intervals, changes in cortical activity within a widespread network of brain regions. These changes, however, do not encompass a core memory region, namely the ventromedial prefrontal cortex (vmPFC). Here, I discuss research showing that the neural activity of the vmPFC is sensitive to the remoteness of memories, especially using tasks that involve autobiographical recollection. Taken together, these findings appear to highlight a differential contribution of the vmPFC according to the nature of the to-be-remembered material (laboratory vs. autobiographical) that might be further investigated by future research.

摘要

Tallman 及其同事（本期）表明，即使在很短的时间间隔内，实验室材料的记忆巩固也会在广泛的大脑区域网络中产生皮质活动的变化。然而，这些变化不包括核心记忆区域，即腹内侧前额叶皮层 (vmPFC)。在这里，我讨论的研究表明 vmPFC 的神经活动对记忆的遥远性很敏感，尤其是使用涉及自传回忆的任务时。总而言之，这些发现似乎突出了 vmPFC 根据待记忆材料的性质（实验室与自传）的不同贡献，未来研究可能会进一步研究这些材料。