Importance Large-scale genome-wide association studies (GWASs) are expected to inform the development of pharmacological treatments, however the mechanisms of correspondence between the genetic liability identified through GWASs and disease pathophysiology are not well understood.

中文翻译：

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将 GWAS 与精神疾病的药物治疗联系起来

大规模全基因组关联研究 (GWAS)有望为药物治疗的发展提供信息，但通过 GWAS 确定的遗传倾向与疾病病理生理学之间的对应机制尚不清楚。