ABSTRACT

Ultra-high molecular weight polyethylene (UHMWPE) materials have played a significant role in the field of reconstructive surgery, particularly as acetabular liners/sockets for total hip joint replacement (THR), and tibial inserts for total knee joint replacement (TKR). This review aims to provide a perspective on key elements regarding the processing–structure–property relationship of UHMWPE and derivatives. Much emphasis will be provided to discuss the clinically relevant properties of UHMWPE blend/composite formulation, Vitamin-E reinforced or highly crosslinked variants. In addition, we provide clinical insights into the role of wear debris in inflammation and osteolysis. The relatively unexplored domain of UHMWPE additive manufacturing. Finally, the relatively unexplored domain of UHMWPE additive manufacturing and the opportunities associated with the next generation of UHMWPE implants are highlighted.

摘要

超高分子量聚乙烯 (UHMWPE) 材料在重建手术领域发挥了重要作用，特别是作为全髋关节置换术 (THR) 的髋臼内衬/窝和全膝关节置换术 (TKR) 的胫骨衬垫。本综述旨在提供有关 UHMWPE 及其衍生物的加工-结构-性能关系的关键要素的观点。将重点讨论 UHMWPE 混合/复合配方、维生素 E 增强或高度交联变体的临床相关特性。此外，我们提供了关于磨损碎片在炎症和骨质溶解中的作用的临床见解。UHMWPE 增材制造相对未开发的领域。最后，