ABSTRACT

There have been two dominating theories for memory consolidation: the standard model (SM) and multiple trace theory (MTT). Whereas lesion studies have largely indicated a waning role for the hippocampus in memory consolidation, and thus have supported SM, findings from neuroimaging studies have produced varying results. Tallman et al. (this issue) argue that this variability may result from confounding factors and that, once these factors are accounted for, their neuroimaging results support SM. They do not, however, consider a third option: the unified theory. Here, we suggest that their findings, along with neurobiochemical and engram cell studies, may better fit this third theory.

摘要

记忆巩固有两种主要理论：标准模型 (SM) 和多迹理论 (MTT)。虽然损伤研究在很大程度上表明海马体在记忆巩固中的作用减弱，因此支持 SM，但神经影像学研究的结果产生了不同的结果。塔尔曼等人。（本期）认为这种可变性可能是由混杂因素引起的，并且一旦考虑到这些因素，他们的神经影像学结果就支持 SM。然而，他们没有考虑第三种选择：统一理论。在这里，我们建议他们的发现，连同神经生化和印迹细胞研究，可能更符合第三种理论。