Aims: To analyze disparities in age at death and cause-specific mortality in a sample of patients registered with alcohol use disorders (AUDs) in state-run addiction treatment centers in Novosibirsk, Russia. Methods: Database: 92,269 deaths recorded by medical facilities in Novosibirsk between 2000 and 2010, comprising cause of death (per ICD-10), sex, and date of birth and death. Average age at death and proportion of cause-specific deaths were compared between patients (n =1,762) treated for AUDs as a primary diagnosis and the general population, the latter derived from deaths recorded by all medical facilities.Results: The average age at death was significantly lower (p < .001) in patients compared with the general population; men lived, on average, 8.4 years fewer; for women, this difference was 19.7 years. The pronounced gender gap in age at death in the general population (12.7 years) disappeared in the patient sample. They incurred proportionally more deaths because of infectious diseases, injuries, poisonings, diseases of the digestive system, and certain cardiovascular diseases such as cardiomyopathies. They incurred proportionally fewer deaths due to chronic ischemic heart disease, myocardial infarction, cerebrovascular diseases, and neoplasms.Conclusions: Compared to the general population, cause-specific mortality in AUD patients was high in categories largely contributing to a premature death. Specific measures including screenings for alcohol problems in primary health care and early interventions to reduce level of drinking should be a priority.

中文翻译：

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俄罗斯新西伯利亚国营服务机构接受酒精使用障碍治疗的患者的病因特异性死亡率

目的：分析在俄罗斯新西伯利亚国营成瘾治疗中心登记的酒精使用障碍 (AUD) 患者样本中死亡年龄和特定原因死亡率的差异。方法：数据库：新西伯利亚医疗机构在 2000 年至 2010 年间记录的 92,269 例死亡，包括死因（根据 ICD-10）、性别、出生日期和死亡日期。比较了将 AUD 作为主要诊断治疗的患者 (n = 1,762) 与一般人群的平均死亡年龄和特定原因死亡的比例，后者来自所有医疗机构记录的死亡人数。结果：平均死亡年龄与普通人群相比，患者显着降低 (p < .001)；男性平均少活 8.4 年；对于女性来说，这一差异为 19.7 岁。一般人群（12.7 岁）死亡年龄的明显性别差距在患者样本中消失了。他们因传染病、受伤、中毒、消化系统疾病和某些心血管疾病（如心肌病）而导致的死亡人数相应增加。他们因慢性缺血性心脏病、心肌梗塞、脑血管疾病和肿瘤而导致的死亡人数相应减少。结论：与一般人群相比，AUD 患者的原因特异性死亡率在很大程度上导致过早死亡的类别中较高。具体措施包括在初级卫生保健中筛查酒精问题和降低饮酒水平的早期干预措施应该是优先事项。他们因传染病、受伤、中毒、消化系统疾病和某些心血管疾病（如心肌病）而导致的死亡人数相应增加。他们因慢性缺血性心脏病、心肌梗塞、脑血管疾病和肿瘤而导致的死亡人数相应减少。结论：与一般人群相比，AUD 患者的原因特异性死亡率在很大程度上导致过早死亡的类别中较高。具体措施包括在初级卫生保健中筛查酒精问题和降低饮酒水平的早期干预措施应该是优先事项。他们因传染病、受伤、中毒、消化系统疾病和某些心血管疾病（如心肌病）而导致的死亡人数相应增加。他们因慢性缺血性心脏病、心肌梗塞、脑血管疾病和肿瘤而导致的死亡人数相应减少。结论：与一般人群相比，AUD 患者的原因特异性死亡率在很大程度上导致过早死亡的类别中较高。具体措施包括在初级卫生保健中筛查酒精问题和降低饮酒水平的早期干预措施应该是优先事项。他们因慢性缺血性心脏病、心肌梗塞、脑血管疾病和肿瘤而导致的死亡人数相应减少。结论：与一般人群相比，AUD 患者的原因特异性死亡率在很大程度上导致过早死亡的类别中较高。具体措施包括在初级卫生保健中筛查酒精问题和降低饮酒水平的早期干预措施应该是优先事项。他们因慢性缺血性心脏病、心肌梗塞、脑血管疾病和肿瘤而导致的死亡人数相应减少。结论：与一般人群相比，AUD 患者的原因特异性死亡率在很大程度上导致过早死亡的类别中较高。具体措施包括在初级卫生保健中筛查酒精问题和降低饮酒水平的早期干预措施应该是优先事项。