The Triple Helix of university-industry-government interactions, highlighting the enhanced role of the university in the transition from industrial to knowledge-based society, has become widespread in innovation and entrepreneurship studies. We analyze classic literature and recent research, shedding light on the theoretical development of a model that has engendered controversy for being simultaneously analytical and normative, theoretical, practical and policy-relevant. We identify lacunae and suggest future analytical trajectories for theoretical development of the Triple Helix model. The explanatory power of Triple Helix has been strengthened by integrating various social science concepts, e.g. Simmel’s triad, Schumpeter’s organizational entrepreneur, institutional logics and social networks, into its framework. As scholars and practitioners from various disciplinary and inter-disciplinary research fields, e.g. artificial intelligence, political theory, sociology, professional ethics, higher education, regional geography and organizational behavior join Triple Helix studies or find their perspectives integrated, new directions appear for Triple Helix research.

大学-产业-政府互动的三重螺旋，突出了大学在从工业社会向知识型社会转型中的增强作用，已在创新和创业研究中广泛存在。我们分析了经典文献和最近的研究，揭示了一个模型的理论发展，该模型因同时具有分析性和规范性、理论性、实践性和政策相关性而引起争议。我们确定了缺陷并为三螺旋模型的理论发展提出了未来的分析轨迹。通过将各种社会科学概念，如齐美尔的三元组、熊彼特的组织企业家、制度逻辑和社会网络等纳入其框架，三螺旋的解释力得到了加强。