The possible direct role of exercise intensity and duration on leptin concentrations is conflicting. The aim of this study was to evaluate the acute effects of high intensity interval (HIIE) and moderate intensity continuous (MICE) exercise on plasma leptin response. Seven young volunteers underwent three tests: 1) a treadmill graded exercise test to identify running peak velocity (PV); 2) HIIE: 5 × 2 min work bouts at 90% of PV, interspersed by 2 min of passive recovery and; 3) MICE: 30 min at 70 % of PV. Blood samples were drawn for the assays of leptin before and 30 minutes after HIIE and MICE. A 2-way repeated measures ANOVA showed a significant main effect of time [F(1,6) =17,52; p=0,006], no significant effect of condition (type of exercise) (F(1,6) = 0,16; p = 0,68) and no significant interaction (condition × time) (F(1,6)= 0,48, p=0,51). Leptin decreased 30 min after HIIE (t= 2,95, p=0,025) and MICE (t=4,18; p=0,005). There was no difference between the HIIE and MICE conditions immediately after exercise (t=0,90; p=0,40). After HIIE and MICE, leptin decreased in the same magnitude. It appears that both exercise modalities result in physical stress which is sufficient to improve short-term leptin sensibility.

中文翻译：

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高强度间歇和中等强度连续跑步后的急性瘦素反应

运动强度和持续时间对瘦素浓度的可能直接作用是相互矛盾的。本研究的目的是评估高强度间歇 (HIIE) 和中等强度连续 (MICE) 运动对血浆瘦素反应的急性影响。七名年轻志愿者接受了三项测试：1）跑步机分级运动测试，以确定跑步峰值速度（PV）；2) HIIE：90% PV 时进行 5 × 2 分钟的训练，穿插 2 分钟的被动恢复；3) MICE：70% PV 时 30 分钟。在 HIIE 和 MICE 之前和之后 30 分钟抽取血样用于瘦素测定。2 路重复测量 ANOVA 显示出显着的时间主效应 [F(1,6) =17,52; p = 0,006]，条件（运动类型）没有显着影响（F（1,6）= 0,16; p = 0,68）并且没有显着的相互作用（条件×时间）（F（1,6）= 0,48, p = 0,51)。HIIE (t= 2,95, p=0,025) 和 MICE (t=4,18; p=0,005) 后 30 分钟瘦素下降。运动后立即 HIIE 和 MICE 条件之间没有差异（t=0,90；p=0,40）。在 HIIE 和 MICE 之后，瘦素下降幅度相同。似乎这两种运动方式都会导致身体压力，足以改善短期瘦素敏感性。