Abstract In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40–70 min for trisubstituted imidazoles and 30–40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92–98% for trisubstituted imidazoles and 94–98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free conditions, high catalytic activity, shorter reaction time, easy recovery by an external magnet, high purity, and excellent yields are some features of these reactions.

中文翻译：

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磁性纳米粒子负载磺酸作为绿色催化剂在无溶剂条件下一锅法合成 2,4,5-三取代咪唑和 1,2,4,5-四取代咪唑

摘要 在这项工作中，磁性纳米粒子负载的磺酸（γ-Fe2O3-SO3H）作为一种高效的催化剂在短时间内合成了 2,4,5-三取代咪唑和 1,2,4,5-四取代咪唑。在简单的多组分反应中获得了时间（三取代咪唑为 40-70 分钟，四取代咪唑为 30-40 分钟）和高纯度产物（三取代咪唑为 92-98%，四取代咪唑为 94-98%）。这些产物的结构通过 FT-IR 和 NMR 确认。绿色和可回收的催化剂、环保和无溶剂条件、高催化活性、更短的反应时间、易于通过外部磁铁回收、高纯度和优异的收率是这些反应的一些特点。