Naphthalene, a Polycyclic Aromatic Hydrocarbon is widely used as a fumigant and disinfectant despite its toxic effect and is ranked as the ninth most threatening compound. The present study was carried out to determine the in vivo effect of naphthalene at different concentrations on acetylcholinesterase (AChE) enzyme activity in different tissues of Anabas testudineus. The fishes were exposed to varying concentrations of naphthalene (4.2 mgL–1, 4.4 mgL–1, 4.6 mgL–1, 4.8 mgL–1 and 5 mgL–1) for a period of 72 hours. Acetylcholinesterase enzyme activity was found to be significantly inhibited, in a dose-response manner. The inhibition percentage of AChE activity varied from 9.34–43.95% in brain tissue, 2.56–35.81% in liver tissue, 5.94–34.15% in muscle tissue and 3.92–33.75% in gills in comparison to the tissues of the control group. Maximum inhibition of acetylcholinesterase enzyme activity in treated fish was observed in the brain followed by liver, muscles, and gills. This study highlights the significance and role of acetylcholinesterase as a potential stress biomarker of naphthalene toxicity.

中文翻译：

---

乙酰胆碱酯酶，作为萘毒性的潜在生物标志物，在淡水长尾鱼的不同组织中，ANABAS TESTUDINEUS

萘是一种多环芳烃，尽管具有毒性，但仍被广泛用作熏蒸剂和消毒剂，并被列为第九大威胁化合物。本研究旨在确定不同浓度的萘在体内对鱼腥藻不同组织中乙酰胆碱酯酶 (AChE) 酶活性的影响。将这些鱼暴露在不同浓度的萘（4.2 mgL-1、4.4 mgL-1、4.6 mgL-1、4.8 mgL-1 和 5 mgL-1）中 72 小时。发现乙酰胆碱酯酶活性以剂量反应的方式被显着抑制。与对照组的组织相比，脑组织中 AChE 活性的抑制百分比为 9.34-43.95%，肝组织中为 2.56-35.81%，肌肉组织中为 5.94-34.15%，鳃中为 3.92-33.75%。在处理过的鱼的大脑中观察到乙酰胆碱酯酶活性的最大抑制，其次是肝脏、肌肉和鳃。本研究强调了乙酰胆碱酯酶作为萘毒性潜在应激生物标志物的重要性和作用。