Objectives: Differentiation of infection from sterile inflammation is still a major concern for clinicians. The ¹⁸F-WBC positron emission tomography/computed tomography scan has been considered a promising tool for accurate diagnosis of infection owing to its high specificity, but it renders the availability of a medical cyclotron a necessity. The aim of the present study was to determine the feasibility of labeling leukocytes and establish the protocol in a center without the availability of an on-site medical cyclotron. The secondary aim was to monitor radiation doses to occupational workers involved in labeling of leukocytes with ¹⁸F-FDG.

中文翻译：

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在没有现场回旋加速器的中心对白细胞进行 18F-FDG 标记的可行性以及在标记过程中对职业工人的辐射剂量监测

目的：区分感染与无菌性炎症仍然是临床医生的主要关注点。¹⁸ F-WBC 正电子发射断层扫描/计算机断层扫描由于其高度特异性而被认为是准确诊断感染的有前途的工具，但它使得医疗回旋加速器的可用性成为必要。本研究的目的是确定标记白细胞的可行性，并在没有现场医疗回旋加速器的情况下在中心建立协议。次要目的是监测涉及用¹⁸ F-FDG 标记白细胞的职业工人的辐射剂量。