Extensive research has elucidated the influence of the gut microbiota on human health and disease susceptibility and resistance. We review recent clinical and laboratory-based experimental studies associating the gut microbiota with certain human diseases. We also highlight ongoing translational advances that manipulate the gut microbiota to treat human diseases and discuss opportunities and challenges in translating microbiome research from and to the bedside.

中文翻译：

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将微生物组研究转化为临床

广泛的研究已经阐明了肠道微生物群对人类健康以及疾病易感性和抵抗力的影响。我们回顾了最近基于肠道微生物群与某些人类疾病相关的临床和实验室实验研究。我们还重点介绍了操纵肠道微生物群来治疗人类疾病的持续转化进展，并讨论了将微生物组研究转化为临床的机遇和挑战。