Studies of word class processing have found verb retrieval impairments in individuals with primary progressive aphasia (Bak et al., 2001; Cappa et al., 1998; Cotelli et al., 2006; Hillis, Heidler-Gary, et al., 2006; Hillis, Oh, & Ken, 2004; Marcotte et al., 2014; Rhee, Antiquena, & Grossman, 2001; Silveri & Ciccarelli, 2007; Thompson, Lukic, et al., 2012) associated primarily with the agrammatic variant. However, fewer studies have focused on verb comprehension, with inconsistent results. Because verbs are critical to both production and comprehension of clauses and sentences, we investigated verb processing across domains in agrammatic, logopenic, and semantic PPA and a group of age-matched healthy controls. Participants completed a confrontation naming task for verb production and an eye-tracking word-picture matching task for online verb comprehension. All PPA groups showed impaired verb production and comprehension relative to healthy controls. Most notably, the PPA-S group performed more poorly than the other two PPA variants in both domains. Overall, the results indicate that semantic deficits in the PPA-S extend beyond object knowledge to verbs as well, adding to our knowledge concerning the nature of the language deficits in the three variants of primary progressive aphasia.

词类处理研究发现原发性进行性失语症患者的动词检索障碍（Bak et al., 2001; Cappa et al., 1998; Cotelli et al., 2006; Hillis, Heidler-Gary, et al., 2006; Hillis, Oh, & Ken, 2004; Marcotte et al., 2014; Rhee, Antiquena, & Grossman, 2001; Silveri & Ciccarelli, 2007; Thompson, Lukic, et al., 2012) 主要与语法变体相关。然而，很少有研究关注动词理解，结果不一致。因为动词对从句和句子的产生和理解都至关重要，我们研究了语法、对数开放和语义 PPA 以及一组年龄匹配的健康对照中跨域的动词处理。参与者完成了动词产生的对抗命名任务和在线动词理解的眼球追踪词图匹配任务。相对于健康对照组，所有 PPA 组都表现出动词产生和理解受损。最值得注意的是，PPA-S 组在两个域中的表现都比其他两个 PPA 变体差。总体而言，结果表明，PPA-S 中的语义缺陷也超出了对象知识，也扩展到了动词，增加了我们对原发性进行性失语症三种变体中语言缺陷性质的认识。