Recent studies in both human and experimental animals have identified fragmented and unpredictable parental and environmental signals as a novel source of early-life adversity. Early-life unpredictability may be a fundamental developmental factor that impacts brain development, including reward and emotional memory circuits, affecting the risk for psychopathology later in life. Here, we tested the hypothesis that self-reported early-life unpredictability is associated with psychiatric symptoms in adult clinical populations.

中文翻译：

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早期生活的不可预测性对成年期神经精神症状模式的影响

最近对人类和实验动物的研究发现，支离破碎且不可预测的父母和环境信号是早期生活逆境的一个新来源。生命早期的不可预测性可能是影响大脑发育的一个基本发育因素，包括奖赏和情绪记忆回路，影响晚年患精神病理学的风险。在这里，我们检验了这样一个假设：自我报告的早期生活的不可预测性与成人临床人群的精神症状相关。