Phenylthiocarbamide (PTC) sensitivity, a sensory trait mediated by the bitter taste receptor 38 (TAS2R38), has been described as a promising biomarker of health status or disease risk. The aim of this cross-sectional study was to evaluate the influence of PTC phenotypes on (1) individual anthropometric and clinical history variables; (2) other basic taste recognition thresholds (RTs), and (3) the hedonic perception and habitual intake of Brassicaceae vegetables in a young adult population (18.9 ± 1.7 years old). The PTC phenotype was determined by the quantitative measure of the PTC recognition threshold (non-tasters, 24.1%; tasters, 52.3%; and super tasters, 23.6%). No significant differences in smoking habits, oral and nasal disorders, family antecedents of diseases related to metabolic syndrome, and Brassicaceae vegetable hedonic perception and consumption were found between the PTC phenotype groups. The average BMI of super-taster females and males was significantly lower compared to non-tasters. In addition, the PTC taster status was a predictor of lower scores for other basic taste RTs. Overall, the defined PTC super-taster cohort could be differentiated from the non-tasters by variables related to weight control such as BMI and sucrose RT.

中文翻译：

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苯硫脲感知与人体测量变量以及对苦味蔬菜的摄入和喜好的关联

苯硫脲 (PTC) 敏感性是一种由苦味受体 38 (TAS2R38) 介导的感觉特性，已被描述为健康状况或疾病风险的有希望的生物标志物。这项横断面研究的目的是评估 PTC 表型对 (1) 个体人体测量学和临床病史变量的影响；(2) 其他基本味觉识别阈值 (RT)，以及 (3) 年轻人（18.9 ± 1.7 岁）对十字花科蔬菜的享乐感知和习惯性摄入。PTC 表型通过 PTC 识别阈值的定量测量来确定（非品尝者，24.1%；品尝者，52.3%；和超级品尝者，23.6%）。在吸烟习惯、口腔和鼻腔疾病、代谢综合征相关疾病的家族前因方面没有显着差异，在 PTC 表型组之间发现了十字花科蔬菜的享乐感知和消费。与非品酒者相比，超级品酒者的女性和男性的平均 BMI 显着降低。此外，PTC 品尝者状态是其他基本口味 RT 得分较低的预测指标。总体而言，定义的 PTC 超级品尝者群组可以通过与体重控制相关的变量（例如 BMI 和蔗糖 RT）与非品尝者区分开来。