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Potential Clinical Applications for Continuous Ketone Monitoring in the Hospitalized Patient with Diabetes
Current Diabetes Reports ( IF 4.2 ) Pub Date : 2022-08-19 , DOI: 10.1007/s11892-022-01489-6
Michelle Jaromy 1 , Joshua D Miller 2
Affiliation  

Purpose of Review

In this review, the authors discuss potential clinical applications for continuous ketone monitoring (CKM) in a broad continuum of clinical settings from pre-hospital care and the emergency department to acute inpatient management and post-discharge follow-up.

Recent Findings

Though in its early stages, the concept of a novel continuous ketone sensing technology exerts great potential for use in the detection and hospital management of DKA, namely to overcome diagnostic barriers associated with ketoacidosis in patients with diabetes and obtain real-time BOHB levels, which may be useful in understanding both patients’ response to treatment and DKA trajectory. Peri- and intra-operative use of CKM technology can potentially be applied in a number of urgent and elective surgical procedures frequently underwent by patients with diabetes and in the observation of patients during peri-operative fasting. In transitional care management, CKM technology could potentially facilitate patients’ safe transition through levels of care, following hospital discharge from a DKA episode.

Summary

This evaluation of the literature presents the potential advantages of adopting CKM and integrating this technology into the care algorithm of patients at risk for ketoacidosis.



中文翻译:

糖尿病住院患者持续酮体监测的潜在临床应用

审查目的

在这篇综述中,作者讨论了连续酮监测 (CKM) 在从院前护理和急诊科到急性住院管理和出院后随访的广泛临床环境中的潜在临床应用。

最近的发现

虽然处于早期阶段,但新型连续酮体传感技术的概念在 DKA 的检测和医院管理中具有巨大的应用潜力,即克服与糖尿病患者酮症酸中毒相关的诊断障碍并获得实时 BOHB 水平,这可能有助于了解患者对治疗的反应和 DKA 轨迹。CKM 技术的围手术期和围手术期使用可潜在地应用于糖尿病患者经常进行的许多紧急和选择性外科手术以及围手术期禁食期间的患者观察。在过渡性护理管理中,CKM 技术可能有助于患者在 DKA 发作出院后安全过渡到护理水平。

概括

对文献的评估展示了采用 CKM 并将该技术整合到有酮症酸中毒风险患者的护理流程中的潜在优势。

更新日期:2022-08-19
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