Chronic periodontitis can lead to alveolar bone resorption and eventually tooth loss. Stem cells from exfoliated deciduous teeth (SHED) are appropriate bone regeneration seed cells. To track the survival, migration, and differentiation of the transplanted SHED, we used super paramagnetic iron oxide particles (SPIO) Molday ION Rhodamine-B (MIRB) to label and monitor the transplanted cells while repairing periodontal bone defects.

中文翻译：

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在大鼠牙周骨再生过程中，用 Molday ION Rhodamine-B 标记的人类脱落乳牙干细胞的追踪。

慢性牙周炎可导致牙槽骨吸收并最终导致牙齿脱落。来自脱落的乳牙 (SHED) 的干细胞是合适的骨再生种子细胞。为了追踪移植 SHED 的存活、迁移和分化，我们使用超顺磁性氧化铁颗粒 (SPIO) Molday ION Rhodamine-B (MIRB) 在修复牙周骨缺损的同时标记和监测移植细胞。