This study aimed to identify determinants of adherence to lifestyle and body weight recommendations for cancer prevention among Lynch Syndrome (LS) patients. Cross-sectional baseline data of LS patients participating in the Lifestyle & Lynch (LiLy) study was used to assess determinants of adherence to the World Cancer Research Fund cancer prevention recommendations on body weight, physical activity, and red and processed meat intake. Adherence and potential determinants of adherence were assessed using questionnaires. Multivariable logistic regression analyses were conducted to identify determinants of adherence. Of the 211 participants, 50.2% adhered to the body weight recommendation, 78.7% adhered to the physical activity recommendation, and 33.6% adhered to the red and processed meat recommendation. Being younger and having a higher level of education were associated with adherence to the recommendation on body weight. Having knowledge about the recommendation was associated with adherence to the recommendations on physical activity and red and processed meat. Results confirm that knowledge about recommendations for cancer prevention is an important determinant for adherence and suggest that strategies to increase knowledge should be included in lifestyle promotion targeted at LS patients, along with behavior change techniques influencing other modifiable determinants.

本研究旨在确定林奇综合征 (LS) 患者遵守生活方式和体重建议以预防癌症的决定因素。参与 Lifestyle & Lynch (LiLy) 研究的 LS 患者的横断面基线数据用于评估遵守世界癌症研究基金会关于体重、体育活动以及红肉和加工肉类摄入量的癌症预防建议的决定因素。使用问卷评估依从性和依从性的潜在决定因素。进行多变量逻辑回归分析以确定依从性的决定因素。在 211 名参与者中，50.2% 遵守体重建议，78.7% 遵守体育锻炼建议，33.6% 遵守红肉和加工肉类建议。更年轻和受教育程度更高与遵守体重建议有关。了解该建议与遵守有关身体活动以及红肉和加工肉类的建议有关。结果证实，关于癌症预防建议的知识是依从性的重要决定因素，并表明增加知识的策略应包括在针对 LS 患者的生活方式促进中，以及影响其他可修改决定因素的行为改变技术。