Conductive layered materials such as MXenes (e.g., transition metal carbides, nitrides, and carbonitrides), graphene and their derivatives have attracted tremendous research interests in diverse fields of research for their unique structured merits and outstanding physical and chemical properties. Benefitting from their unique layered structures and fascinating multifunctional characteristic, MXenes and graphene serve as vital components in a variety of wearable devices. Especially, due to their large surface area and high electrocatalytic activity, these materials have also demonstrated great promise in biophysical and biochemical sensing systems. Following an introduction into the field, we summarize the recent progress in wearable sensors that can be accomplished by using layered materials, with a specific focus on kinematic, mechanical, thermal, pressure and strain sensors. A further large section underscores the recent progress in MXenes and graphene based wearable biochemical sensors including electrolyte monitoring, glucose monitoring, micro/mcromolecular organics metabolite, volatile gases monitoring and humidity sensors. The next section covers the sensing of small biomolecules serving as biomarkers, which are of great significance for early diagnosis and treatment of a spectrum of diseases. This review underscores the recent progress in wearable sensors to be used in different physiological and environmental signals. Finally, the review concludes with a debate on current challenges being faced and future perspectives.

导电层状材料，例如 MXenes（例如，过渡金属碳化物、氮化物和碳氮化物）、石墨烯及其衍生物以其独特的结构优点和突出的物理化学性能在各个研究领域引起了巨大的研究兴趣。得益于其独特的分层结构和迷人的多功能特性，MXenes 和石墨烯成为各种可穿戴设备的重要组成部分。特别是，由于它们的大表面积和高电催化活性，这些材料在生物物理和生化传感系统中也显示出巨大的前景。在对该领域进行介绍之后，我们总结了可通过使用分层材料实现的可穿戴传感器的最新进展，特别关注运动学、机械、热、压力和应变传感器。另一大节强调了基于 MXenes 和石墨烯的可穿戴生化传感器的最新进展，包括电解质监测、葡萄糖监测、微/大分子有机物代谢物、挥发性气体监测和湿度传感器。下一节将介绍作为生物标志物的小生物分子的传感，这对于一系列疾病的早期诊断和治疗具有重要意义。这篇综述强调了用于不同生理和环境信号的可穿戴传感器的最新进展。最后，审查以关于当前面临的挑战和未来前景的辩论结束。挥发性气体监测和湿度传感器。下一节将介绍作为生物标志物的小生物分子的传感，这对于一系列疾病的早期诊断和治疗具有重要意义。这篇综述强调了用于不同生理和环境信号的可穿戴传感器的最新进展。最后，审查以关于当前面临的挑战和未来前景的辩论结束。挥发性气体监测和湿度传感器。下一节将介绍作为生物标志物的小生物分子的传感，这对于一系列疾病的早期诊断和治疗具有重要意义。这篇综述强调了用于不同生理和环境信号的可穿戴传感器的最新进展。最后，审查以关于当前面临的挑战和未来前景的辩论结束。