Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells that Are Defective in Self-Renewal.,International Journal of Stem Cells

当前位置： X-MOL 学术 › Int. J. Stem Cells › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells that Are Defective in Self-Renewal.
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2022-10-31 , DOI: 10.15283/ijsc22138
Bong Jong Seo ₁ , Tae Kyung Hong _{1,

2} , Sang Hoon Yoon _{1,

2} , Jae Hoon Song ₁ , Sang Jun Uhm ₃ , Hyuk Song ₁ , Kwonho Hong ₁ , Hans Robert Schöler ₄ , Jeong Tae Do _{1,

2}

Affiliation

DNA methyltransferases (Dnmts) play an important role in regulating DNA methylation during early developmental processes and cellular differentiation. In this study, we aimed to investigate the role of Dnmts in neural differentiation of embryonic stem cells (ESCs) and in maintenance of the resulting neural stem cells (NSCs).

中文翻译：

缺乏 DNA 甲基转移酶的胚胎干细胞分化为自我更新有缺陷的神经干细胞。

DNA 甲基转移酶 (Dnmts) 在早期发育过程和细胞分化过程中调节 DNA 甲基化中起重要作用。在这项研究中，我们旨在研究 Dnmts 在胚胎干细胞 (ESC) 的神经分化和维持由此产生的神经干细胞 (NSC) 中的作用。

更新日期：2022-10-31

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>