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Quick guide to secondary metabolites from Apiospora and Arthrinium
Fungal Biology Reviews ( IF 6 ) Pub Date : 2022-11-03 , DOI: 10.1016/j.fbr.2022.10.001
Marie L. Overgaard , Trine Aalborg , Emil J. Zeuner , Klaus R. Westphal , Frederik A. Lau , Vibeke S. Nielsen , Kasper B. Carstensen , Emil A. Hundebøll , Tia A. Westermann , Gustav G. Rathsach , Jens L. Sørensen , Jens C. Frisvad , Reinhard Wimmer , Teis E. Sondergaard

Apiospora and Arthrinium have undergone a period of upheaval with disparate phylogenic affiliation during the past ten years. Recently, they were divided into two separate clades with the majority being Apiospora and several species changing genus from Arthrinum to Apiospora. The first genome annotation became available in 2020, and the potential for novel secondary metabolite production appears very high in these yet unexplored genera compared to other more famous filamentous fungi. In this review, we present the current state of knowledge of 269 secondary metabolites isolated from the two fungal genera combined and highlight some of the compounds with known biological or toxic effects.



中文翻译:

Apiospora 和 Arthrinium 次生代谢物快速指南

在过去的十年中,Apiospora 和 Arthrinium经历了一段具有不同系统发育隶属关系的剧变时期。最近,它们被分为两个独立的进化枝,其中大多数是蜂属和几个物种,从属到蜂孢属。第一个基因组注释于 2020 年推出,与其他更著名的丝状真菌相比,这些尚未开发的属中产生新的次级代谢物的潜力似乎非常高。在这篇综述中,我们介绍了从两个真菌属中分离出的 269 种次级代谢物的最新知识状态,并重点介绍了一些具有已知生物学或毒性作用的化合物。

更新日期:2022-11-03
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