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Effects of patient-controlled analgesia using dexmedetomidine combined with sufentanil on caesarean section and hemodynamics
Indian Journal of Chemical Technology ( IF 0.5 ) Pub Date : 2022-11-18
Wei Li, Ying Zhang, Jianrui Lv, Yong Zhang, Bin Luo

This study evaluates the effects of patient-controlled analgesia (PCA) using dexmedetomidine combined with sufentanil on caesarean section and maternal hemodynamics. In this study, a total of 140 eligible puerperal are randomly divided into control and experimental groups (n=70). Control group has received PCA using sufentanil, while experimental group has received PCA using dexmedetomidine plus sufentanil. The analgesic and sedative effects have been evaluated using Bruggemann comfort scale(BCS) score and Ramsay score, respectively. Maternal hemodynamics-related indices heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and oxyhemoglobin saturation (SpO2) have been detected at the end of operation (T0), upon access to analgesic pump (T1), 24 h after access to analgesic pump (T2) and 48h after access to analgesic pump (T3). The incidence rates of postoperative complications were compared. It has been found that at T2 and T3, BCS and Experimental group had significantly higher Ramsay score and lower HR, SBP, DBP and SpO2 than those of control group (P<0.05). The incidence rate of complications in experimental group (5.71%) is found to be significantly lower than that of control group (22.86%) (P<0.05).

中文翻译:

右美托咪定联合舒芬太尼自控镇痛对剖宫产术及血流动力学的影响

本研究评估使用右美托咪定联合舒芬太尼的患者自控镇痛 (PCA) 对剖宫产和产妇血流动力学的影响。在这项研究中,共有 140 名符合条件的产褥期患者被随机分为对照组和实验组 (n=70)。对照组接受使用舒芬太尼的PCA,而实验组接受使用右美托咪定加舒芬太尼的PCA。镇痛和镇静作用分别采用Bruggemann舒适量表(BCS)评分和Ramsay评分进行评价。产妇血流动力学相关指标心率(HR)、收缩压(SBP)、舒张压(DBP)和氧合血红蛋白饱和度(SpO2)已在手术结束(T0)、接入镇痛泵(T1)时检测到, 使用镇痛泵 (T2) 后 24 小时和使用镇痛泵 (T3) 后 48 小时。比较术后并发症的发生率。结果发现,T2、T3时,BCS组和实验组Ramsay评分显着高于对照组,HR、SBP、DBP、SpO2显着低于对照组(P<0.05)。结果发现,实验组并发症发生率(5.71%)明显低于对照组(22.86%)(P<0.05)。
更新日期:2022-11-20
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