Knockdown of DAPK1 inhibits IL-1β-induced inflammation and cartilage degradation in human chondrocytes by modulating the PEDF-mediated NF-kB and NLRP3 inflammasome pathway,Innate Immunity

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Knockdown of DAPK1 inhibits IL-1β-induced inflammation and cartilage degradation in human chondrocytes by modulating the PEDF-mediated NF-kB and NLRP3 inflammasome pathway
Innate Immunity ( IF 3.2 ) Pub Date : 2022-11-21 , DOI: 10.1177/17534259221086837
Zhongyuan Zhao ₁ , Wei Liu ₂ , Gong Cheng ₃ , Shengjie Dong ₁ , Yuchi Zhao ₁ , Hao Wu ₃ , Zhilin Cao ₃

Affiliation

Osteoarthritis (OA) is a common joint disease that is characterized by inflammation and cartilage degradation. Death-associated protein kinase 1 (DAPK1) is a multi-domain serine/threonine kinase an...

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